Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10604053 | Carbohydrate Polymers | 2012 | 5 Pages |
Abstract
⺠In the current work, O-CMC-metformin nanoparticles were prepared and characterized. ⺠The potential of the same against pancreatic cancer cells were analyzed in vitro. ⺠MTT assay showed preferential toxicity of nanoparticles on pancreatic cancer cells. ⺠Uptake of the nanoparticles by pancreatic cancer cells and normal cells were confirmed by imaging. ⺠This nanoformulation can be a therapeutic for both pancreatic cancer and diabetes.
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Authors
K.S. Snima, R. Jayakumar, A.G. Unnikrishnan, Shantikumar. V. Nair, Vinoth-Kumar Lakshmanan,