Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10604143 | Carbohydrate Polymers | 2012 | 7 Pages |
Abstract
⺠Insoluble cyclodextrin polymers as discs with a controlled geometry have been synthesized. ⺠Interaction between the polymers and model drugs in the solid state canbe evidenced. ⺠Kinetic, diffusion constants and diffusion coefficients have been calculated. ⺠In vitro drug release studies followed a simple Fickian diffusion mechanism. ⺠The synthesized matrices are potentially suitable as sustained release systems.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Rubén MachÃn, José Ramón Isasi, Itziar Vélaz,