| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10604214 | Carbohydrate Polymers | 2012 | 5 Pages |
Abstract
⺠We developed doxorubicin loaded pH responsive chitin nanogels (Dox-CNGs) for cancer drug delivery applications. ⺠The in vitro cytotoxicity studies of 130-160 nm sized Dox-CNGs proved their cyto compatibility with L929 and toxicity towards PC3, MCF-7, A549 and HEPG2 cancer cells. ⺠The internalization of the Dox-CNGs showed a significant uptake of the Dox-CNGs in all the tested cell lines. ⺠These results indicated that Dox-CNGs can be used for prostate, breast, lung and liver cancer.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
R. Jayakumar, Amrita Nair, N. Sanoj Rejinold, S. Maya, S.V. Nair,