Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10604314 | Carbohydrate Polymers | 2011 | 10 Pages |
Abstract
- Electrostatic complexes are formed between hyaluronan and hyaluronidase at pH 3-10.
- At 6 °C, sedimentable slightly charged and soluble highly charged complexes exist.
- One HAase molecule is associated with 23-71 HA carboxyl groups, depending on pH.
- The pI value for hyaluronidase has been estimated to 5.3.
- Positive patches on the HAase molecule allow the complex formation at pH 7.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hélène Lenormand, Fériel Amar-Bacoup, Jean-Claude Vincent,