Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10605615 | Carbohydrate Research | 2011 | 13 Pages |
Abstract
For the investigation of glycosidases, and for the construction of glycan arrays the p-nitrophenyl- and p-aminophenyl glycosides of mucin O-glycan core structures 1-7 and the 2,6-ST-antigen have been chemically synthesized using d-galactose as a precursor for GalNAc residues. GlcNAc residues have partly been introduced using a 4,6-di-O-benzoyl-2,3-N,O-oxazolidinone-protected donor, which allowed deprotection of the formed di- and tri-saccharides in one step using sodium methoxide.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Martin Hollinger, Fana Abraha, Stefan Oscarson,