| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10606616 | Carbohydrate Research | 2011 | 6 Pages |
Abstract
A water-soluble glucan, isolated from the alkaline extract of the fruit bodies of an edible mushroom, Lentinus squarrosulus (Mont.) Singer was found to consist of (1â3,6)-linked, (1â3)-linked, (1â6)-linked, and terminal β-d-glucopyranosyl moieties in a relative proportion of approximately 1:2:1:1. This polysaccharide showed optimum activation of macrophages as well as splenocytes and thymocytes at 10 μg/mL. Structural investigation was carried out using sugar analysis, methylation analysis, periodate oxidation study, and NMR experiments (1H, 13C, DEPT-135, DQF-COSY, TOCSY, NOESY, ROESY, HMQC, and HMBC). On the basis of above-mentioned experiments, the structure of the repeating unit of the polysaccharide was established as:
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Authors
Sanjoy Kumar Bhunia, Biswajit Dey, Kankan K. Maity, Sukesh Patra, Soumitra Mandal, Swatilekha Maiti, Tapas K. Maiti, Samir R. Sikdar, Syed S. Islam,