| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10612698 | Journal of Controlled Release | 2015 | 31 Pages |
Abstract
Although cationic lipid mixtures can bind equivalent amounts of DNA the different stabilities against biological agents (proteoglycans, DNase) are also efficiency determining factors that should not be underestimated in the field of lipofection.235
Keywords
DLS1,2-dioleoyl-sn-glycero-3-phosphoserineTris–Acetate–EDTARFUDOPCDOPSLipofectionGAGsA.U.EtBrIEPDPPCLipoplexeseGFPpDNAPBSCHOLCLSMSDSFBS1,2-dioleoyl-sn-glycero-3-phosphoethanolamine2-(N-morpholino)ethanesulfonic acidIRRASN/P ratioethidium bromidestandard deviationTransfection efficiencycharge densityTAEsupporting informationCell viabilitysodium dodecyl sulfatefetal bovine serumIntensityHydrodynamic radiusInfrared reflection–absorption spectroscopyPhosphate buffered salinePhospholipidsCationic lipidsMeSconfocal laser scanning microscopyIsoelectric pointarbitrary unitsRelative Fluorescence UnitsDynamic Light Scatteringenhanced green fluorescent proteinPlasmid DNADOPEGene therapycholesterolGlycosaminoglycans
Related Topics
Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
Christopher Janich, Christian Wölk, Frank Erdmann, Thomas Groth, Gerald Brezesinski, Bodo Dobner, Andreas Langner,