Ultrasound-based molecular imaging and specific gene delivery to mesenteric vasculature by endothelial adhesion molecule targeted microbubbles in a mouse model of Crohn's disease

Article ID	Journal	Published Year	Pages	File Type
10613067	Journal of Controlled Release	2013	10 Pages	PDF

Keywords

Sonoporation IBD GALT ICAM-1 MBS ROI VCAM-1 MAdCAM-1 Gene delivery IHC immunohistochemical Uca gut-associated lymphoid tissue Crohn's disease Inflammatory bowel disease tumor necrosis factor alpha intraperitoneal Intravenous Gastrointestinal Endothelial cell Ultrasound contrast agents TNF-α Ultrasound Contrast agents region of interest intercellular adhesion molecule-1 vascular cell adhesion molecule-1 Microbubbles arbitrary units

Related Topics

Physical Sciences and Engineering Materials Science Biomaterials

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Ultrasound-based molecular imaging and specific gene delivery to mesenteric vasculature by endothelial adhesion molecule targeted microbubbles in a mouse model of Crohn's disease

Authors

José L. Tlaxca, Joshua J. Rychak, Peter B. Ernst, Prasad R. Konkalmatt, Talent I. Shevchenko, Theresa T. Pizzaro, Jesús Rivera-Nieves, Alexander L. Klibanov, Michael B. Lawrence,