| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10613392 | Journal of Controlled Release | 2005 | 13 Pages |
Abstract
Gamma irradiation affects either microsphere morphology or the release of OVA as a function of the amount of PEG, and the use of NaCl. Irradiation significantly reduces release rate of protein from the microspheres containing 15% and 30% of PEG and from controls (microspheres without additives), while no significative effect on protein release rate is highlighted on microspheres containing lower amounts of PEG. EPR investigation shows that increasing amounts of PEG up to 30% have a perturbation effect on OVA radiolysis path.
Keywords
Related Topics
Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
Rossella Dorati, Ida Genta, Luisa Montanari, Francesco Cilurzo, Armando Buttafava, Antonio Faucitano, Bice Conti,