| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10613513 | Journal of Controlled Release | 2005 | 19 Pages |
Abstract
Immunization of mice was performed using plasmids encoding immunodominant antigens of Listeria monocytogenes adsorbed onto RG 502 HÂ +Â PEI 10% microparticles. The efficiency was tested by intravenous challenge with an otherwise lethal dose of L. monocytogenes. PLGAÂ +Â PEI microspheres can be used as adjuvant delivery systems for DNA but further optimization is necessary to exploit their full potential.
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Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
C.G. Oster, N. Kim, L. Grode, L. Barbu-Tudoran, A.K. Schaper, S.H.E. Kaufmann, T. Kissel,