Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10613544 | Journal of Controlled Release | 2005 | 15 Pages |
Abstract
The introduction of bulky aromatic/hydrophobic (tryptophan) or hydrophillic (serine) moieties into the positively charged vectors allows the compacted particles to disperse into salt-containing medium avoiding salt-induced aggregation. Moreover, tryptophan-containing particles are able to mediate specific gene transfer via receptor-mediated endocytosis.
Keywords
Related Topics
Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
A.G. Gómez-Valadés, M. Molas, A. Vidal-Alabró, J. Bermúdez, R. Bartrons, J.C. Perales,