| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10614866 | Materials Science and Engineering: C | 2011 | 5 Pages |
Abstract
Poly(ethylene glycol) decorated poly(methyl methacrylate) particles were synthesized by means of emulsion polymerization using poly(ethylene glycol) sorbitan monolaurate (Tween-20) as surfactant. PMMA/PEG particles presented mean diameter (195 ± 15) nm, indicating narrow size distribution. The adsorption behavior of bovine serum albumin (BSA) and concanavalin A (ConA) onto PMMA/PEG particles was investigated by means of spectrophotometry. Adsorption isotherms obtained for BSA onto PMMA/PEG particles fitted well sigmoidal function, which is typical for multilayer adsorption. Con A adsorbed irreversibly onto PMMA/PEG particles. The efficiency of ConA covered particles to induce dengue virus quick agglutination was evaluated.
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Authors
Alfredo Bonfá, Rafael S.N. Saito, Rafael F.O. França, Benedito A.L. Fonseca, Denise F.S. Petri,