| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10614917 | Materials Science and Engineering: C | 2011 | 5 Pages |
Abstract
To meet the challenges of designing an injectable scaffold and regenerating bone with complex three-dimensional (3D) structures, a biomimetic and injectable hydrogel scaffold based on nano-hydroxyapatite (HA), collagen (Col) and chitosan (Chi) is synthesized. The chitosan/nano-hydroxyapatite/collagen (Chi/HA/Col) solution rapidly forms a stable gel at body temperature. It shows some features of natural bone both in main composition and microstructure. The Chi/HA/Col system can be expected as a candidate for workable systemic minimally invasive scaffolds with surface properties similar to physiological bone based on scanning electron microscopic (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR) results.
Related Topics
Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
Zhi Huang, Qingling Feng, Bo Yu, Songjian Li,