Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10614971 | Materials Science and Engineering: C | 2013 | 10 Pages |
Abstract
⺠Nicotine-magnesium aluminum silicate microparticles were prepared using electrostatic interaction. ⺠Lyophilization was used for drying and maintaining an original morphology of the microparticles. ⺠Chitosan (CS) was used for surface modification of the microparticles at acidic pH. ⺠Surface modification using CS caused an increase in release and permeation of nicotine. ⺠Microparticle surface-modified with CS presented better mucoadhesive properties.
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Authors
Watchara Kanjanakawinkul, Thomas Rades, Satit Puttipipatkhachorn, Thaned Pongjanyakul,