Article ID Journal Published Year Pages File Type
10614971 Materials Science and Engineering: C 2013 10 Pages PDF
Abstract
► Nicotine-magnesium aluminum silicate microparticles were prepared using electrostatic interaction. ► Lyophilization was used for drying and maintaining an original morphology of the microparticles. ► Chitosan (CS) was used for surface modification of the microparticles at acidic pH. ► Surface modification using CS caused an increase in release and permeation of nicotine. ► Microparticle surface-modified with CS presented better mucoadhesive properties.
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Physical Sciences and Engineering Materials Science Biomaterials
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