Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10615192 | Materials Science and Engineering: C | 2005 | 6 Pages |
Abstract
The preosteoblastic cell line MC3T3-E1, derived from mouse calvariae, was used to test for biocompatibility in cell culture experiments. The cells were seeded on the scaffolds immersed in the culture medium and cultured for 2 weeks. Thereafter the cells on the scaffold were fixed and investigated by histological methods. The osteoblast-like cells were found to cover the whole external and internal surface of the scaffold, they were embedded in collagenous extracellular matrix. The cells had in particular the tendency to fill any crack or opening and to generally smooth the exposed surfaces.
Keywords
Related Topics
Physical Sciences and Engineering
Materials Science
Biomaterials
Authors
A. Woesz, M. Rumpler, J. Stampfl, F. Varga, N. Fratzl-Zelman, P. Roschger, K. Klaushofer, P. Fratzl,