Autopsy standards for fetal lengths and organ weights of an Australian perinatal population

SummaryAimsThis study aims to establish a complete and accurate set of Australian reference ranges to be used during the routine perinatal post-mortem examination. Eighteen routinely measured parameters will be analysed for each gestational age from 12 weeks to 42 weeks inclusive.MethodsA retrospective review was performed of all perinatal and neonatal autopsies conducted at the Royal Women’s Hospital (RWH), Melbourne, between 1 January 2001 and 31 December 2006. A total of 1116 post-mortem examination reports were analysed for this study. Established study design, technical and statistical methodologies were followed.ResultsReference ranges comprising mean and standard deviation have been produced, together with the 5th, 50th and 95th percentiles for all parameters at each gestational age. Graphs demonstrating these data have been developed for each parameter.ConclusionThis study has established a complete set of reference ranges for parameters measured at perinatal postmortem examinations. As the sample population used is truly representative of the mixed immigrant population present in Australian society, the reference ranges and percentiles produced in this study will be valuable for all perinatal pathologists.