| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10672554 | Ultramicroscopy | 2011 | 6 Pages |
Abstract
⺠Successful development of protocols for the quantum dot tagging of cell membrane proteins. ⺠Successful implementation of scanning near-field optical microscopy to image cell membranes and accurately define the location of the tagged E-cadherin protein. ⺠Compare and contrast data with that in the literature regarding the role of proteins in cell adhesion mechanisms. ⺠Analysis of the data and our experimental experiences have demonstrated the practical benefits of quantum dots over Alexa 488, a conventional fluorophore. ⺠Data highlights the various stages of cell confluency to illustrate the variation in E-cadherin location in cells involved in cell-to-cell adhesion.
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Authors
K.-A.D. Walker, S.H. Doak, P.R. Dunstan,