Article ID Journal Published Year Pages File Type
10690608 Ultrasonics 2013 7 Pages PDF
Abstract
► Sonodynamic therapy (SDT) is a new treatment strategy for malignant glioma. ► Glioma stem-like cells overexpressing the ABCG2 transporter were generated. ► ABCG2 decreased the antitumor effect of SDT by sonosensitizer efflux. ► Sonosensitizer extrusion by ABCG2 was inhibited by fumitremorgin C. ► Fumitremorgin C improved the antitumor efficacy of SDT in glioma stem-like cells.
Keywords
Related Topics
Physical Sciences and Engineering Physics and Astronomy Acoustics and Ultrasonics
Preview
The ABCG2 transporter is a key molecular determinant of the efficacy of sonodynamic therapy with Photofrin in glioma stem-like cells
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