Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10691576 | Ultrasound in Medicine & Biology | 2014 | 9 Pages |
Abstract
The speed of sound correlates well with the fat content of the liver. Therefore, non-invasive quantification of sound speed in the liver might be of diagnostic value. Here we describe a new non-invasive method that would be clinically applicable for measurement of sound speed in the liver. Sprague-Dawley rats were divided into two groups: a control group and a fatty liver group prepared by keeping the rats on a choline-deficient diet for 6Â wk. The livers were subjected to pathologic and biochemical analysis; the speed of sound through the liver tissue was measured using our proposed method and a pulser-receiver as standard. Our results indicated that use of the proposed method makes it feasible to diagnose fatty liver with good accuracy on the basis of sound speed. This approach would have considerable potential for non-invasive diagnosis of fatty liver and would be a valuable adjunct to conventional liver diagnostic procedures.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Acoustics and Ultrasonics
Authors
Hideki Kumagai, Koji Yokoyama, Kimito Katsuyama, Shoji Hara, Hiroaki Yamamoto, Takanori Yamagata, Nobuyuki Taniguchi, Norio Hirota, Kouichi Itoh,