| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10694485 | Advances in Space Research | 2011 | 11 Pages |
Abstract
Further, the cell morphology, activity, proliferation, and differentiation of osteoclasts and osteoblasts exposed to hypergravity were evaluated in vitro. Hypergravity inhibited actin ring formation in mature osteoclasts, which suggested that the osteoclast activity was suppressed. However, hypergravity had no effect on osteoblasts. These results suggest that hypergravity can stimulate an increase in bone volume by suppressing bone resorption in ovariectomized rats.
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Authors
Tesshu Ikawa, Amu Kawaguchi, Takahiro Okabe, Tadashi Ninomiya, Yuko Nakamichi, Midori Nakamura, Shunsuke Uehara, Hiroaki Nakamura, Nobuyuki Udagawa, Naoyuki Takahashi, Hiroaki Nakamura, Shigeyuki Wakitani,