Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10710511 | Journal of Magnetism and Magnetic Materials | 2005 | 5 Pages |
Abstract
The dissociation of apoferritin into subunits at pH 2 followed by its reformation at pH 7.4 in the presence of doxorubicin-HCl gives rise to a solution containing five doxorubicin-HCl molecules trapped within the apoferritin. This is the first report showing that ferritin can encapsulate an anti-cancer drug into its cavity.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Condensed Matter Physics
Authors
Ece Simsek, Mehmet Akif Kilic,