Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10715897 | Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment | 2010 | 6 Pages |
Abstract
A simple and improved digital timing method was developed for positron emission tomography (PET). This method, the so-called 'initial rise interpolation method', is based on an important characteristic of gamma signals: a properly pre-amplified and sampled gamma signal pulse can be characterized to arrive with an initial rise from the baseline and then reach a maximum rise. The pulse arrival time was obtained by calculating the intersection of the initial rise line with the baseline for each gamma signal pulse. Using an 8-channel 100Â MHz free-running ADC and FPGA combined data acquisition (DAQ) card, three digital timing methods were employed to measure the coincidence timing resolution of two types of recently developed 3Â mmÃ3Â mm PET sensors (a fast and a slow GAPD). The results showed that the initial rise interpolation method provides the best timing resolution for both types of GAPDs: 0.7Â ns FWHM for fast GAPD and 1.5Â ns FWHM for slow GAPD (digital CFD: 1.5 and 2.2Â ns FWHM; maximum rise interpolation: 1.8 and 2.7Â ns FWHM). By implementing the initial rise interpolation method into the FPGA of DAQ card, PET images of two 18F line sources were acquired successfully using a pair of 4Ã4 GAPD-LYSO array detectors (single pixel size: 3Â mmÃ3Â mm). The acquired image spatial resolution was a 3.1Â mm FWHM. Furthermore, the simulation was performed to evaluate the effects of the pulse rise time, pulse amplitude and front-end noise level on the timing resolution estimated using the three digital timing methods. In accordance with the measurement results, the simulation results also showed that the initial rise interpolation method provided the best timing resolution. These results show that this simple and improved digital timing method is reliable and useful for the development of high performance PET.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Instrumentation
Authors
Wei Hu, Yong Choi, Key Jo Hong, Jihoon Kang, Jin Ho Jung, Youn Suk Huh, Hyun Keong Lim, Sang Su Kim, Byung Jun Min, Byung-Tae Kim,