Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10730176 | Applied Radiation and Isotopes | 2005 | 14 Pages |
Abstract
In this study, the response to ionsing radiation of the normoxic polymer gel dosimeter comprising tetrakis (hydroxymethyl) phosphonium chloride (THPC) with methacrylic acid (MAA) and gelatin, named MAGAT, has been investigated. Using magnetic resonance imaging (MRI), the R2-dose response or change in R2 (ÎR2) is evaluated for different concentrations of the component chemicals: THPC, MAA, gelatin and hydroquinone (HQ). The formulation for which the MAGAT polymer gel dosimeter had a maximum response was determined, and the spatial and temporal stability for this formulation analyzed. It was found that the formulation that provided the greatest change in R2 was 10Â mM THPC, 0-0.05Â mM HQ, 6-7% gelatin and 4-6% MAA (evaluated one day post-irradiation). MAGAT polymer gel dosimeters comprising 10Â mM THPC, 0.05Â mM HQ, 6-9% MAA and 4-6% gelatin have shown potential for use in radiation therapy dosimetry.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
C. Hurley, A. Venning, C. Baldock,