Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10730974 | Physica Medica | 2016 | 6 Pages |
Abstract
With multi-parametric MRI it becomes feasible to revisit the GTV-CTV concept in radiotherapy of prostate cancer. While detection of index lesions is quite reliable, contouring variability and the low sensitivity to small lesions suggest that the remainder of the prostate should be treated as CTV. Clinical trials that investigate the options for dose differentiation, for example with dose escalation to the visible tumor or dose reduction to the CTV, are therefore warranted.
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Authors
Cuong V. Dinh, Peter Steenbergen, Ghazaleh Ghobadi, Stijn W.T.J.P. Heijmink, Floris J. Pos, Karin Haustermans, Uulke A. van der Heide,