Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10736563 | Ageing Research Reviews | 2015 | 15 Pages |
Abstract
- mRNA translation is mainly regulated at the initiation phase and influences ageing.
- Non-coding RNAs and RNA binding proteins control and fine-tune mRNA homeostasis.
- Intrinsic RNA properties are altered during ageing.
- Protein synthesis is regulated by key pathways that modulate ageing, such as the insulin/IGF and TOR signalling cascades.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Nikolaos Charmpilas, Ioanna Daskalaki, Margarita Elena Papandreou, Nektarios Tavernarakis,