Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10736582 | Ageing Research Reviews | 2013 | 8 Pages |
Abstract
⺠BMP4 and Noggin play key roles in the proliferation/quiescence balance of the neural stem cells in the adult hippocampus. ⺠The hippocampal neurogenesis is changed in AD. ⺠BMP4 and Noggin are disturbed in the hippocampus of AD patients. ⺠Modulating hippocampus neurogenesis through BMP4/Noggin pathway possibly represents a promising strategy for AD therapy.
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Authors
Haiwei Xu, Wei Huang, Yanjiang Wang, Weizhong Sun, Jun Tang, Dabing Li, Pei Xu, Liang Guo, Zheng Qin Yin, Xiaotang Fan,