Article ID Journal Published Year Pages File Type
10736586 Ageing Research Reviews 2013 13 Pages PDF
Abstract
► AD pathology leads to sleep disturbances and circadian disruptions. ► Sleep disturbances have a negative influence on the quality of life of patients and care givers. ► Sleep deprivation and hypocretin increase Aβ levels and plaque deposition. ► Melatonin has anti-amyloidgenic properties. ► Important role of both melatonin and hypocretin in modulating AD pathophysiology.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Authors
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