Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10736593 | Ageing Research Reviews | 2013 | 6 Pages |
Abstract
⺠We raise that CKIP-1 acts as a scaffold adaptor mediating interactions with multiple proteins. ⺠We summarize the different ways and conditions through which CKIP-1 functions. ⺠We emphasize that CKIP-1 is involved in various important signaling pathways, controlling cell growth, apoptosis and differentiation. ⺠We discuss the structure, limitation and predict that CKIP-1 will be a promising target for treatment of osteoporosis, and cancers.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Jing Nie, Lin Liu, Fuchu He, Xiaobing Fu, Weidong Han, Lingqiang Zhang,