Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10736605 | Ageing Research Reviews | 2013 | 9 Pages |
Abstract
⺠The Free Radical Theory (FRT) of ageing is most studied in invertebrates. ⺠Evidence for FRT driving ageing is stronger in Drosophila, weaker in C. elegans. ⺠Likely order of importance to ageing is oxidative damage to proteins, lipids, DNA. ⺠In intervention studies, oxidative damage has been measured too infrequently. ⺠Use inducible systems or drugs to avoid confounding developmental effects.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
David Clancy, John Birdsall,