| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10736607 | Ageing Research Reviews | 2013 | 7 Pages |
Abstract
⺠MicroRNAs regulate lifespan through the control of conserved genetic pathways. ⺠MicroRNAs respond to environmental perturbations. ⺠Age-associated microRNAs predict for future longevity. ⺠tRNA-derived shorter fragments have a new regulatory role in the stress response. ⺠The RNA editing machinery acts in double-stranded RNA-mediated gene silencing. ⺠These multiple layers in gene regulatory mechanisms may stabilize genetic networks in ageing.
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Authors
Masaomi Kato, Frank J. Slack,