| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10736660 | Ageing Research Reviews | 2005 | 27 Pages |
Abstract
Implications of the function of CRF-BP for therapeutic strategies in MDD are being discussed. An important advantage of ligands that target CRF-BP is that concentrations of free CRF can be altered without acting directly on the transmission of CRF through its receptor.
Keywords
ACTHMDDCRFCRF-BPCRFRCorticotropin-releasing factor-binding proteinAVPDSTMajor depressive disorderStressDepressionImmune systemCNScentral nervous systemcorticotropin-releasing factorPVNCSFCerebrospinal fluidHPA axisparaventricular nucleusadrenocorticotropic hormonearginine vasopressinCorticotropin-releasing factor receptor
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Filip Van Den Eede, Christine Van Broeckhoven, Stephan J. Claes,