Article ID Journal Published Year Pages File Type
10737923 Free Radical Biology and Medicine 2012 9 Pages PDF
Abstract
► Thioredoxin-1 (Trx1) physically interacts with the SARAH domain of MST1. ► Trx1 inhibits the reactive oxygen species-induced homodimerization of MST1. ► Trx1 negatively regulates the oxidative stress-induced activation of MST1.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Thioredoxin-1 functions as a molecular switch regulating the oxidative stress-induced activation of MST1
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