| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10737928 | Free Radical Biology and Medicine | 2012 | 14 Pages |
Abstract
⺠We reviewed studies on biomarkers related to oxidative stress in autism. ⺠Glutathione (GSH), transmethylation, and transsulfuration pathways were altered. ⺠Blood GSH, glutathione peroxidase, methionine, and cysteine decreased, whereas blood oxidized glutathione increased. ⺠No association with blood vitamin levels was found. ⺠Carriers of the mutant C677T allele in the MTHFR gene had higher risk of autism.
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Authors
Alessandra Frustaci, Monica Neri, Alfredo Cesario, James B. Adams, Enrico Domenici, Bernardo Dalla Bernardina, Stefano Bonassi,