| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10737942 | Free Radical Biology and Medicine | 2017 | 11 Pages |
Abstract
⺠Muscle Trx1 and Trx2 redox potentials vary between nucleus, cytosol, and mitochondria. ⺠Oxidants modified nuclear and cytosolic Trx1 and GSH but not mitochondrial Trx2. ⺠Aging increased muscle Trx contents, but did not affect Trx redox potentials. ⺠Contractile activity affected muscle GSH but not Trx content or redox potentials. ⺠Glutathione in muscle is more susceptible to physiological oxidation than Trx's.
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Authors
Ivan Dimauro, Timothy Pearson, Daniela Caporossi, Malcolm J. Jackson,