Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10737947 | Free Radical Biology and Medicine | 2012 | 11 Pages |
Abstract
⺠The radical probe CT02-H specifically reacts with O2
- â forming a quinone methide. ⺠O2
- â rapidly reacts with CT02-H with decreased EPR signal, enabling O2
- â detection. ⺠HPLC with EC detection can detect <0.2 pmol of the quinone methide product. ⺠CT02-H can measure O2
- â generation as low as 0.34 nM/min in an enzyme or cell system. ⺠With EPR spectroscopy, CT02-H can simultaneously measure O2
- â and O2.
- â forming a quinone methide. ⺠O2
- â rapidly reacts with CT02-H with decreased EPR signal, enabling O2
- â detection. ⺠HPLC with EC detection can detect <0.2 pmol of the quinone methide product. ⺠CT02-H can measure O2
- â generation as low as 0.34 nM/min in an enzyme or cell system. ⺠With EPR spectroscopy, CT02-H can simultaneously measure O2
- â and O2.
Keywords
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Authors
Yangping Liu, Yuguang Song, Francesco De Pascali, Xiaoping Liu, Frederick A. Villamena, Jay L. Zweier,