| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10737952 | Free Radical Biology and Medicine | 2012 | 15 Pages |
Abstract
⺠Elevated steatosis arises following short-term fatty acid dosage. ⺠Arachidonic acid showed greater reactive oxygen species production than palmitate. ⺠Free fatty acids impair ATP synthesis. ⺠Free fatty acids impair mitochondrial function. ⺠Ethanol and free fatty acids induce greater hepatic damage than fatty acids alone.
Keywords
PPAR-αDCFDARCRΔΨmFCCPFFAFADH22′,7′-dichlorofluorescein diacetateALDArachidonic acidFree fatty acidFatty acidsAlcoholalcoholic liver diseaseARARh 123Free radicalsRhodamine 123electron transport chainMitochondriaNADHrespiratory control ratioETcPalmitic acidMembrane potentialMitochondrial membrane potentialperoxisome proliferator-activated receptor-αreduced nicotinamide adenine dinucleotide
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Daniel Gyamfi, Hannah E. Everitt, Ihab Tewfik, Dahn L. Clemens, Vinood B. Patel,