| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10737958 | Free Radical Biology and Medicine | 2012 | 9 Pages |
Abstract
⺠GSTM1 gene expression, function, and regulation are reviewed. ⺠GSTM1 acts through interactions with other genes and environmental factors. ⺠Pharmacologic and genetic manipulation of the GSTM1 gene is discussed.
Keywords
NF-κBDEPsMEKK1glutathione S-transferase mu 1NQO1IL-8GSTM1ETsGSHNrf2Jnkc-Jun N-terminal kinaseNAD(P)H:quinone oxidoreductase 1ROSAir pollutionLung inflammationInterleukin 8COPDChronic obstructive pulmonary diseaseenvironmental tobacco smokeDiesel exhaust particlesFree radicalsNF-E2-related factor 2antioxidant-responsive elementnuclear factor κBAREASKGlutathioneReactive oxygen species
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Authors
Weidong Wu, David Peden, David Diaz-Sanchez,