| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10737969 | Free Radical Biology and Medicine | 2012 | 9 Pages |
Abstract
⺠The nitrate-nitrite-NO pathway is a physiological source of NO. ⺠Nitrite exerts antihypertensive effects. ⺠Nitrite is reduced to NO under the acidic conditions of the stomach. ⺠Omeprazole increases gastric pH and reduces the hypotensive effects of nitrite. ⺠Omeprazole may blunt beneficial cardiovascular effects of dietary nitrite.
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Authors
Lucas C. Pinheiro, Marcelo F. Montenegro, Jefferson H. Amaral, Graziele C. Ferreira, Alisson M. Oliveira, Jose E. Tanus-Santos,