Article ID Journal Published Year Pages File Type
10737973 Free Radical Biology and Medicine 2012 10 Pages PDF
Abstract
► The role of TGIF in the progression of UC was studied. ► AKT1 overexpression promotes cellular Nox2/p67phox activation and invasive ability. ► TGIF induces superoxide generation from Nox2/p67phox via the PI3K/AKT pathway. ► TGIF-induced superoxide generation enhances migration/invasion ability of UC cells.
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Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
TG-interacting factor-induced superoxide production from NADPH oxidase contributes to the migration/invasion of urothelial carcinoma
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