Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10737977 | Free Radical Biology and Medicine | 2012 | 10 Pages |
Abstract
⺠4-(2-Cyclohexylethoxy) aniline (IM3829) inhibits expression of Nrf2 mRNA. ⺠Suppression of Nrf2 by IM3829 accumulates ionizing radiation-induced reactive oxygen species. ⺠IM3829 enhances radiosensitivity of non-small-cell lung cancer cells. ⺠IM3829 could potentially act as an effective adjuvant for radiotherapy.
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Authors
Saelooom Lee, Min-Jin Lim, Mi-Hyoung Kim, Chi-Ho Yu, Yeon-Sook Yun, Jiyeon Ahn, Jie-Young Song,