Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10737998 | Free Radical Biology and Medicine | 2012 | 12 Pages |
Abstract
⺠Photoinduced generation of side-chain tyrosyl radicals of αS produces covalent soluble oligomers. ⺠Dityrosine crosslinked oligomers of α-synuclein decrease the yield of mature amyloid fibrils. ⺠Dityrosine crosslinked oligomers of α-synuclein are cytotoxic.
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Authors
Claudio D. Borsarelli, Lisandro J. Falomir-Lockhart, Veronika Ostatná, Jonathan A. Fauerbach, He-Hsuan Hsiao, Henning Urlaub, Emil PaleÄek, Elizabeth A. Jares-Erijman, Thomas M. Jovin,