| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10738053 | Free Radical Biology and Medicine | 2012 | 9 Pages |
Abstract
⺠Stable HO-1 expression in nonerythroid cells does not decrease cellular heme. ⺠In such cells iron trafficking into mitochondria and heme synthesis are increased. ⺠Iron-regulatory protein activities and ferritin protein levels are lower owing to increased degradation. ⺠Stable HO-1 expression is associated with elevated cytosolic and mitochondrial O2â
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Authors
Cheng Li, Maria E. Lönn, Xiangcong Xu, Ghassan J. Maghzal, David M. Frazer, Shane R. Thomas, Barry Halliwell, Des R. Richardson, Gregory J. Anderson, Roland Stocker,