Article ID Journal Published Year Pages File Type
10738092 Free Radical Biology and Medicine 2012 10 Pages PDF
Abstract
► Nitric oxide regulates mitochondrial respiration by inhibiting cytochrome c oxidase. ► Inorganic nitrate and nitrite can form NO and other bioactive nitrogen oxides in vivo. ► Complexes in the mitochondrial electron transport system can reduce nitrite to NO. ► Dietary nitrate improves mitochondrial efficiency and exercise performance. ► The therapeutic aspects of the nitrate-nitrite-NO pathway are currently being investigated.
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Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
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