Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10738092 | Free Radical Biology and Medicine | 2012 | 10 Pages |
Abstract
⺠Nitric oxide regulates mitochondrial respiration by inhibiting cytochrome c oxidase. ⺠Inorganic nitrate and nitrite can form NO and other bioactive nitrogen oxides in vivo. ⺠Complexes in the mitochondrial electron transport system can reduce nitrite to NO. ⺠Dietary nitrate improves mitochondrial efficiency and exercise performance. ⺠The therapeutic aspects of the nitrate-nitrite-NO pathway are currently being investigated.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Filip J Larsen, Tomas A Schiffer, Eddie Weitzberg, Jon O Lundberg,