| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10738096 | Free Radical Biology and Medicine | 2012 | 9 Pages |
Abstract
⺠4-Hydroxy-E-globularinin (4-HEG) is a natural molecule isolated from the medicinal plant Premna integrifolia. ⺠We examined the life span of wild-type N2 Caenorhabditis elegans and daf-16, sir-2.1, and mev-1 mutants. ⺠4-HEG reduced reactive oxygen species levels and fat accumulation in the worms. ⺠4-HEG extended the life span of worms via DAF-16 activation.
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Authors
Virendra Shukla, Deepti Yadav, Suresh C. Phulara, M.M. Gupta, Shilpi K. Saikia, Rakesh Pandey,