| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10738102 | Free Radical Biology and Medicine | 2012 | 13 Pages |
Abstract
⺠O2
- â upregulation in breast cancer cells is an estrogen receptor (ER)-dependent phenomenon. ⺠ER effects transient O2
- â upregulation by modulating O2
- â levels within mitochondria of breast cancer cells. ⺠ER-mediated mitochondrial O2
- â upregulation is critical for mTORC2 assembly/activation in breast cancer cells.
- â upregulation in breast cancer cells is an estrogen receptor (ER)-dependent phenomenon. ⺠ER effects transient O2
- â upregulation by modulating O2
- â levels within mitochondria of breast cancer cells. ⺠ER-mediated mitochondrial O2
- â upregulation is critical for mTORC2 assembly/activation in breast cancer cells.
Keywords
N-acetyl-l-cysteineCYP 3A4mTORC2MnTBAPERENACFBSEGF17-β-estradiolO2•−ROSsuperoxide anionsuperoxide anionsdihydroethidiumFree radicalsfetal bovine serumcytochrome P450 1A2cytochrome P450 3A4Redox signalingepidermal growth factorMammalian target of rapamycin complex 2DHEReactive oxygen speciesEstrogen receptor
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Authors
Ranjana Kumari Kanchan, Chakrapani Tripathi, Khemraj Singh Baghel, Shailendra Kumar Dwivedi, Balawant Kumar, Sabyasachi Sanyal, Sharad Sharma, Kalyan Mitra, Vivek Garg, Kavita Singh, Sarwat Sultana, Raj Kamal Tripathi, Srikanta Kumar Rath,