Article ID Journal Published Year Pages File Type
10738121 Free Radical Biology and Medicine 2012 6 Pages PDF
Abstract
► Calorie restriction (CR) increases eNOS, nNOS, and mitochondrial content in brain. ► Serum from CR animals increases nNOS and NO
- in neuronal cultures. ► CR serum enhances mitochondrial biogenesis and respiratory rates in neurons. ► CR serum effects are inhibited by L-NAME and mimicked by the NO
- donor SNAP. ► CR serum and SNAP increase neuronal survival.
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