| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10738130 | Free Radical Biology and Medicine | 2013 | 25 Pages |
Abstract
⺠Inflammation perturbs cellular redox homeostasis and promotes neoplastic transformation. ⺠The tumor microenvironment often maintains an inflammatory state that hastens tumor progression. ⺠Inflammatory mediators induce genomic instability and impair DNA repair mechanisms. ⺠Inflammation causes epithelial-to-mesenchymal transition and accelerates metastasis. ⺠Inflammation disrupts epigenetic control of gene expression and favors tumor growth.
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Authors
Joydeb Kumar Kundu, Young-Joon Surh,