Article ID Journal Published Year Pages File Type
10738132 Free Radical Biology and Medicine 2012 11 Pages PDF
Abstract
► Nox5 activity and expression are increased in IFNγ-exposed human aortic SMCs. ► NF-kB, AP-1, and STAT1/STAT3 regulate Nox5 promoter, Nox5 message, and protein. ► Free radicals generated by up-regulated Nox5 may contribute to vascular dysfunction.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Preview
Positive regulation of NADPH oxidase 5 by proinflammatory-related mechanisms in human aortic smooth muscle cells
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