| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10738140 | Free Radical Biology and Medicine | 2012 | 7 Pages |
Abstract
⺠We evaluated polymorphisms in genes with antioxidant function and lung function phenotypes. ⺠Interactions between variants and cigarette smoking parameters were investigated. ⺠Without consideration of smoking, no variant was associated with lung function. ⺠Results highlight IDH3A, IDH3B, IDH2, and PRDX5 for further investigation.
Keywords
GlrxIDHSEPGSRGCLCFEV1FVCppFEV1MGSTPrdxGSTMicrosomal glutathione S-TransferaseTXNRDAntioxidant enzymesIsocitrate dehydrogenaseCOPDChronic obstructive pulmonary diseasethioredoxin reductaseForced Expiratory Volume in the first secondFree radicalsSODSelenoproteinSuperoxide dismutaseforced vital capacityLung functionPeroxiredoxinglutathione S-transferaseglutathione reductaseGlutaredoxin
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Authors
Amy R. Bentley, Stephen B. Kritchevsky, Tamara B. Harris, Anne B. Newman, Douglas C. Bauer, Bernd Meibohm, Andrew G. Clark, Patricia A. Cassano, for the Health, Aging, Body Composition Study for the Health, Aging, Body Composition Study,