Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10738143 | Free Radical Biology and Medicine | 2012 | 14 Pages |
Abstract
⺠Melatonin ameliorates neural functioning in ischemic-stroke mice. ⺠Melatonin reduces oxidative/inflammatory stress through the MT2 receptor. ⺠Melatonin preserves blood-brain barrier integrity through the MT2 receptor. ⺠Melatonin promotes endogenous neurogenesis through the MT2 receptor. ⺠Melatonin upregulates neurodevelopmental gene expression through the MT2 receptor.
Keywords
DAPIRMCAUniversal Probe LibraryUPLNDSCBFTTCKi67PBSROI2,3,5-triphenyltetrazolium chloride4',6-diamidino-2-phenylindolepositron-emission tomographycerebral blood flowdoublecortindihydroethidiumFree radicalsRhodamine isothiocyanateBBBBlood–brain barrierIschemic strokePhosphate-buffered salineregion of interestNeurogenesisDHEPET
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Authors
Chang-Ming Chern, Jyh-Fei Liao, Yea-Hwey Wang, Yuh-Chiang Shen,